Self-activated <i>in vivo</i> therapeutic cascade of erythrocyte membrane-cloaked iron-mineralized enzymes
Wen Liu, Miaoliang Ruan, Lamei Liu, Xin Ji, Yandong Ma, Pengfei Yuan, Guoheng Tang, Hongsheng Lin, Jian Dai, Wei Xue
Abstract
: Tumor-targeted erythrocyte membrane-cloaked iron-mineralized glucose oxidase (GOx-Fe0@EM-A) exhibits a promising strategy for striking antitumor efficacy by light-driven tumor deep penetration and self-activated therapeutic cascade.
Topics & Concepts
In vivoChemistryEnzymeCell biologyBiochemistryBiophysicsBiologyGeneticsErythrocyte Function and PathophysiologyHemoglobin structure and functionCancer Research and Treatments