Litcius/Paper detail

TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9

Leonhard X. Heinz, JangEun Lee, Utkarsh Kapoor, Felix Kartnig, Vitaly Sedlyarov, Κωνσταντίνος Παπακώστας, Adrián César‐Razquin, Patrick Essletzbichler, Ulrich Goldmann, Adrijana Stefanovic, Johannes W. Bigenzahn, Stefania Scorzoni, Mattia D. Pizzagalli, Ariel Bensimon, André C. Müller, Frederick J. King, Jun Li, Enrico Girardi, M. Lamine Mbow, Charles E. Whitehurst, Manuele Rebsamen, Giulio Superti‐Furga

2020Nature225 citationsDOIOpen Access PDF

Topics & Concepts

TLR7Signal transducing adaptor proteinChemistryCell biologyBiologyReceptorSignal transductionToll-like receptorBiochemistryInnate immune systemImmune Response and InflammationNeutrophil, Myeloperoxidase and Oxidative Mechanismsinterferon and immune responses