Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds
Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Manabu Fujie, Hikaru Suenaga, Haruo Ikeda, Nori Satoh, Kazuo Shin‐ya
Topics & Concepts
PolyketideBiologyBacterial artificial chromosomeHeterologous expressionGene clusterGenePolyketide synthaseStreptomycesHeterologousStreptomyces avermitilisclone (Java method)GeneticsComputational biologyBiosynthesisBacteriaGenomeRecombinant DNAMicrobial Natural Products and BiosynthesisGenomics and Phylogenetic StudiesPlant-Microbe Interactions and Immunity