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Construction of Si‐Stereogenic Silanes through C−H Activation Approach

Long Zheng, Xiao‐Xue Nie, Yichen Wu, Peng Wang

2021European Journal of Organic Chemistry70 citationsDOI

Abstract

Abstract The asymmetric synthesis of Si‐stereogenic silanes has attracted great attention due to the increasing values of Si‐containing functional molecules in synthetic chemistry, medicinal chemistry, and material chemistry. Merging organosilicon chemistry with transition‐metal‐catalyzed C−H approach has led to rich sets of new reactions holding great synthetic values. This Minireview aims to summarize the advances in the construction of Si‐stereogenic silanes through the transition‐metal‐catalyzed C−H activation approach.

Topics & Concepts

SilanesStereocenterOrganosiliconChemistryCatalysisTransition metalOrganic chemistryEnantioselective synthesisSilaneCatalytic C–H Functionalization MethodsOrganoboron and organosilicon chemistryCatalytic Cross-Coupling Reactions
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