Development of VHL-recruiting STING PROTACs that suppress innate immunity
Zhichuan Zhu, Rebecca L. Johnson, Zhigang Zhang, Laura E. Herring, Guochun Jiang, Blossom Damania, Lindsey I. James, Pengda Liu
Topics & Concepts
StingStimulator of interferon genesUbiquitin ligaseInnate immune systemProteasomeAgonistCancer researchCell biologyUbiquitinBiologyImmunologyImmune systemReceptorGeneBiochemistryAerospace engineeringEngineeringinterferon and immune responsesUbiquitin and proteasome pathwaysProtein Degradation and Inhibitors