Metal-Catalyzed Asymmetric Hydrogenation of C═N Bonds
Racha Abed Ali Abdine, Gaspard Hedouin, Françoise Colobert, Joanna Wencel‐Delord
Abstract
This Review recaps the achievements in the field of metal-catalyzed asymmetric direct hydrogenation of nonactivated and activated imines. A summary of the reported catalytic systems with the corresponding reactivity, selectivity, and limitations is given including a discussion about the effects of some reaction conditions on the enantioselectivity of imine hydrogenation. An analysis of proposed imine hydrogenation mechanisms is discussed.
Topics & Concepts
ImineCatalysisReactivity (psychology)SelectivityChemistryMetalAsymmetric hydrogenationCombinatorial chemistryNoyori asymmetric hydrogenationOrganic chemistryEnantioselective synthesisPhotochemistryAlternative medicinePathologyMedicineAsymmetric Hydrogenation and CatalysisSurface Chemistry and CatalysisCatalysis and Hydrodesulfurization Studies