A versatile sensor capable of ratiometric fluorescence detection of trace water and turn-on detection of Cu<sup>2+</sup> modulating the binding interaction of a Cu(<scp>ii</scp>) complex with BSA and DNA complemented by docking studies
S. Vishnu, Anish Nag, A. Das
Abstract
in various types of soils like clay soil, field soil and sand. The interaction of the PBA-Cu(II) complex with transport proteins like bovine serum albumin (BSA) and ct-DNA has been investigated through fluorescence titration experiments. Additionally, the structural optimization of PBA and the PBA-Cu(II) complex has been demonstrated by DFT, and the interaction of the PBA-Cu(II) complex with BSA and ct-DNA has been analyzed using theoretical docking studies.
Topics & Concepts
FluorescenceTRACE (psycholinguistics)ChemistryTurn (biochemistry)PhysicsBiochemistryOpticsLinguisticsPhilosophyMolecular Sensors and Ion DetectionMetal complexes synthesis and propertiesDNA and Nucleic Acid Chemistry