Design, synthesis, docking study, and anticancer evaluation of novel bis-thiazole derivatives linked to benzofuran or benzothiazole moieties as PI3k inhibitors and apoptosis inducers
Ibrahim Taha Radwan, Ahmed H. M. Elwahy, Ahmed F. Darweesh, Marwa Sharaky, Noha Bagato, Hanem F. Khater, Mostafa E. Salem
Topics & Concepts
ChemistryBenzothiazoleCytotoxicityMTT assayBenzofuranDocking (animal)ThiazoleStereochemistryApoptosisCombinatorial chemistryBiochemistryIn vitroMedicineNursingSynthesis and biological activityClick Chemistry and ApplicationsMulticomponent Synthesis of Heterocycles