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Akt-targeted therapy as a promising strategy to overcome drug resistance in breast cancer – A comprehensive review from chemotherapy to immunotherapy

Parham Jabbarzadeh Kaboli, Fatemeh Salimian, Sevil Aghapour, Shixin Xiang, Qijie Zhao, Mingxing Li, Xu Wu, Fukuan Du, Yueshui Zhao, Jing Shen, Chi Hin Cho, Zhangang Xiao

2020Pharmacological Research166 citationsDOI

Topics & Concepts

Protein kinase BBreast cancerMedicineCancer researchCancerLapatinibTriple-negative breast cancerPI3K/AKT/mTOR pathwayWnt signaling pathwayTrastuzumabInternal medicineSignal transductionBiologyBiochemistryCancer Mechanisms and TherapyPI3K/AKT/mTOR signaling in cancerQuinazolinone synthesis and applications
Akt-targeted therapy as a promising strategy to overcome drug resistance in breast cancer – A comprehensive review from chemotherapy to immunotherapy | Litcius