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T cell receptor and cytokine signal integration in CD8+ T cells is mediated by the protein Themis

Joanna Brzostek, Namrata Gautam, Xiang Zhao, Elijah W. Chen, Monika Mehta, Desmond W. H. Tung, Yen Leong Chua, Jiawei Yap, Su H. Cho, Shvetha Sankaran, Vasily Rybakin, Guo Fu, Nicholas R. J. Gascoigne

2020Nature Immunology54 citationsDOI

Topics & Concepts

Cell biologyCD8T cellBiologyCytotoxic T cellT-cell receptorPeripheral toleranceReceptorImmune systemImmunologyBiochemistryIn vitroT-cell and B-cell ImmunologyImmune Cell Function and InteractionCAR-T cell therapy research
T cell receptor and cytokine signal integration in CD8+ T cells is mediated by the protein Themis | Litcius