Litcius/Paper detail

Annulation Reaction of Quinoxalin-2(1<i>H</i>)-ones Initiated by Electrochemical Decarboxylation of <i>N</i>-Arylglycines

Jian-Feng Cui, Weiqiang Zhong, Jing‐Mei Huang

2023The Journal of Organic Chemistry16 citationsDOI

Abstract

A new methodology for the synthesis of tetrahydroimidazo[1,5- a ]quinoxalin-4(5 H )-ones has been accomplished through annulation of quinoxalin-2(1 H )-ones initiated by electrochemical decarboxylation of N -arylglycines catalyzed by ferrocene. With a pair of oxidative and reductive processes occurring among the substrates and intermediates instead of on the electrodes, the electricity consumption was decreased.

Topics & Concepts

DecarboxylationAnnulationElectrochemistryFerroceneChemistryOxidative decarboxylationMedicinal chemistryCombinatorial chemistryElectrodeCatalysisStereochemistryOrganic chemistryPhysical chemistrySynthesis and Biological EvaluationRadical Photochemical ReactionsOxidative Organic Chemistry Reactions