G9a and DNMT1 inhibition modulates CDKN1A promoter methylation and the cell cycle leading to improvement in kidney fibrosis

Yuanyuan Yang, Zijian Zhou, Lujia Wang, Peng Gao, Zhong Wu

2023Biochimica et Biophysica Acta (BBA) - General Subjects10 citationsDOI

Topics & Concepts

DNMT1DNA methylationCancer researchChromatin immunoprecipitationEpigeneticsMethyltransferaseFibrosisBiologyHistone methylationDNA methyltransferaseHistone methyltransferaseKidneyMolecular biologyCell biologyMethylationGene expressionMedicinePromoterInternal medicineEndocrinologyBiochemistryGeneChronic Kidney Disease and DiabetesRenal cell carcinoma treatmentRenal and related cancers