ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449
Andrew E. Sloan, Charles Nock, Xiaobu Ye, Robert Buerki, Susan M. Chang, Glenn J. Lesser, Andrew D. Norden, Timothy F. Cloughesy, Jeffrey J. Olson, Amber Kerstetter-Fogle, Jeremy N. Rich, Joy Fisher, Serena Desideri, Naoko Takebe, William C. Timmer, Stuart A. Grossman, Michael D. Prados
Topics & Concepts
NeurosphereGliomaStem cellInternal medicineSmoothenedOncologyHedgehog signaling pathwayCancer researchMedicinePharmacologyBiologySignal transductionIn vitroEndothelial stem cellAdult stem cellGeneticsBiochemistryHedgehog Signaling Pathway StudiesGlioma Diagnosis and TreatmentCancer-related Molecular Pathways