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Consequences of Abrupt Cessation of Alpha <sub>1</sub> -Antitrypsin Replacement Therapy

Oliver J. McElvaney, Tomás P. Carroll, Alessandro N. Franciosi, James Sweeney, Brian D. Hobbs, Vikita Kowlessar, Cedric Gunaratnam, Emer P. Reeves, Noel G. McElvaney

2020New England Journal of Medicine34 citationsDOI

Abstract

Stopping Therapy for Alpha1-Antitrypsin Deficiency In Ireland, augmentation treatment of patients with genetic alpha1-antitrypsin deficiency was abruptly discontinued when government–industry price...

Topics & Concepts

Alpha 1-antitrypsin deficiencyAlpha (finance)MedicineInternal medicineSurgeryPatient satisfactionConstruct validityProtease and Inhibitor MechanismsBlood Coagulation and Thrombosis Mechanisms
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