Possible therapeutic effects of <i>Nigella sativa</i> and its thymoquinone on COVID-19
Mohammad Reza Khazdair, Shokouh Ghafari, Mahmood Sadeghi
Abstract
CONTEXT: L. (Ranunculaceae) is an annual flowering plant used traditionally as a natural food supplement and multipurpose medicinal agent. OBJECTIVE: , and its constituent, thymoquinone (TQ) on COVID-19 were reviewed. METHODS: , thymoquinone, antiviral effects, anti-inflammatory and immunomodulatory effects in different databases such as Web of Science (ISI), PubMed, Scopus, and Google Scholar were searched from 1990 up to February 2021. RESULTS: and TQ increased the serum levels of IgG1 and IgG2a, and improved pulmonary function tests in restrictive respiratory disorders. DISCUSSION AND CONCLUSIONS: and TQ on infected patients with COVID-19 in randomize clinical trials will be suggested.