Litcius/Paper detail

TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway

John Bosco Ruganzu, Quzhao Zheng, Xiangyuan Wu, Yingying He, Xiaoqian Peng, Hui Jin, Jinsong Zhou, Ruiyang Ma, Shengfeng Ji, Yanbing Ma, Yi‐Hua Qian, Yang Wang, Weina Yang

2020Experimental Neurology114 citationsDOI

Topics & Concepts

TREM2NeuroinflammationMicrogliaGenetically modified mouseSignal transductionTransgeneCell biologyReceptorNeuroscienceBiologyImmunologyInflammationBiochemistryGeneNeuroinflammation and Neurodegeneration MechanismsInflammation biomarkers and pathwaysNeurological Disease Mechanisms and Treatments
TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway | Litcius