Systematic symptom management in the IMPACT Consortium: rationale and design for 3 effectiveness-implementation trials
Ashley Wilder Smith, Lisa DiMartino, Sofia F. Garcia, Sandra A. Mitchell, Kathryn J. Ruddy, Justin D. Smith, Sandra L. Wong, September Cahue, David Cella, Roxanne E. Jensen, Michael J. Hassett, Christine Hodgdon, Anna Kroner, Raymond U. Osarogiagbon, Jennifer Popovic, Kimberly Richardson, Deborah Schrag, Andrea Cheville, David Cella, Andrea Cheville, Michael J. Hassett, Raymond U. Osarogiagbon, Deborah Schrag, Sandra L. Wong, Barbara L Kroner, Ashley Wilder Smith, Lisa DiMartino, Sofia F. Garcia, Joan M. Griffin, Roxanne E. Jensen, Sandra A. Mitchell, Kathryn J. Ruddy, Justin D. Smith, Betina R. Yanez, Jessica Bian, Don S. Dizon, Hannah Hazard‐Jenkins, Mary-Anne Ardini, Paige Ahrens, Jessica D. Austin, Fiona Barrett, Michael Bass, Megan Begnoche, September Cahue, Kimberly Caron, Linda L. Chlan, Ava Coughlin, Christine Cronin, Samira Dias, Nicolas Farisiv, Anne Marie Flores, Martha Garcia, Karla Hemming, Jeph Herrin, Christine Hodgdon, Sheetal Kircher, Kurt Kroenke, Veronica Lam, Nicola Lancki, Quan H Mai, Jennifer Mallow, Nadine J. McCleary, Wynne E. Norton, Mary O’Connor, Deirdre R. Pachman, Loretta Pearsonil, Frank J. Penedo, Jewel Podratz, Jennifer Popovic, Liliana Preiss, Parvez Rahman, Sarah Redmond, James Reich, Joshua E. Richardson, Kimberly Richardson, Jennifer L. Ridgeway, Lila J. Finney Rutten, Karen Schaepe, Denise Scholtens, Tiana Poirier-Shelton, Philip Silberman, Jaclyn Simpson, Laura Tasker, Nathan Tesch, Cindy Tofthagen, Angela C. Tramontano, Benjamin D. Tyndall, Hajime Uno, Firas Wehbe, Bryan J. Weiner
Abstract
Cancer and its treatment produce deleterious symptoms across the phases of care. Poorly controlled symptoms negatively affect quality of life and result in increased health-care needs and hospitalization. The Improving the Management of symPtoms during And following Cancer Treatment (IMPACT) Consortium was created to develop 3 large-scale, systematic symptom management systems, deployed through electronic health record platforms, and to test them in pragmatic, randomized, hybrid effectiveness and implementation trials. Here, we describe the IMPACT Consortium's conceptual framework, its organizational components, and plans for evaluation. The study designs and lessons learned are highlighted in the context of disruptions related to the COVID-19 pandemic.