Spontaneous Tumor Regression in Tasmanian Devils Associated with <i>RASL11A</i> Activation
Mark J. Margres, Manuel Ruiz‐Aravena, Rodrigo Hamede, Kusum Chawla, Austin H. Patton, Matthew Lawrance, Alexandra K. Fraik, Amanda R. Stahlke, Brian W. Davis, Elaine A. Ostrander, Menna E. Jones, Hamish McCallum, Patrick J. Paddison, Paul A. Hohenlohe, David M. Hockenbery, Andrew Storfer
Abstract
Abstract Spontaneous cancer regression in humans is uncommon, but understanding the mechanisms is key for advancing treatment. Using Devil Facial Tumor Disease as a model, Margres et al. employed comparative....
Topics & Concepts
BiologyRegressionGeneticsRegression analysisDiseaseCancerEvolutionary biologyInternal medicineStatisticsPsychologyMedicinePsychoanalysisMathematicsVirus-based gene therapy researchCancer Research and TreatmentsBacteriophages and microbial interactions