Downregulating long non-coding RNA PVT1 expression inhibited the viability, migration and phenotypic switch of PDGF-BB-treated human aortic smooth muscle cells via targeting miR-27b-3p
Shouming Li, Xin Zhao, Shaopeng Cheng, Jialiang Li, Xiao Bai, Xiangbin Meng
Topics & Concepts
Downregulation and upregulationViability assayWestern blotMolecular biologymicroRNAPVT1Platelet-derived growth factor receptorMTT assayChemistryCancer researchCell biologyCell growthBiologyCellGrowth factorLong non-coding RNAGeneBiochemistryReceptorCancer-related molecular mechanisms researchCircular RNAs in diseasesMicroRNA in disease regulation