ALKBH5 facilitates the progression of skin cutaneous melanoma via mediating ABCA1 demethylation and modulating autophagy in an m<sup>6</sup>A-dependent manner
Hanwen Wang, Shixin Zhao, Hengdeng Liu, Yiling Liu, Zihui Zhang, Ziheng Zhou, Peng Wang, Shaohai Qi, Julin Xie
Abstract
A-ABCA1 axis as a potential therapeutic target in SKCM.
Topics & Concepts
BiologyDemethylaseABCA1Downregulation and upregulationCell biologyCancer researchEpigeneticsBiochemistryGeneTransporterRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation