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Discovery of 2,4-diphenyl-substituted thiazole derivatives as PRMT1 inhibitors and investigation of their anti-cervical cancer effects

Ziqi Zhao, Jungan Zhang, Yixin Ren, Luyao Dong, Han Wu, Wei Hong, Huoqiang Huang, Xinyi Yang, Zongran Pang, Hao Wang

2023Bioorganic & Medicinal Chemistry10 citationsDOIOpen Access PDF

Topics & Concepts

HeLaChemistryApoptosisThiazoleMethyltransferaseMethylationCancerCancer cellCancer researchStereochemistryCell cultureBiochemistryCellGeneGeneticsBiologyCancer-related gene regulationEpigenetics and DNA Methylation
Discovery of 2,4-diphenyl-substituted thiazole derivatives as PRMT1 inhibitors and investigation of their anti-cervical cancer effects | Litcius