Discovery of 2,4-diphenyl-substituted thiazole derivatives as PRMT1 inhibitors and investigation of their anti-cervical cancer effects
Ziqi Zhao, Jungan Zhang, Yixin Ren, Luyao Dong, Han Wu, Wei Hong, Huoqiang Huang, Xinyi Yang, Zongran Pang, Hao Wang
Topics & Concepts
HeLaChemistryApoptosisThiazoleMethyltransferaseMethylationCancerCancer cellCancer researchStereochemistryCell cultureBiochemistryCellGeneGeneticsBiologyCancer-related gene regulationEpigenetics and DNA Methylation