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Novel fluoroquinolone hybrids as dual DNA gyrase and urease inhibitors with potential antibacterial activity: Design, synthesis, and biological evaluation

Salah A. Abdel‐Aziz, Katarina Cirnski, Jennifer Herrmann, Mohamed A. A. Abdel‐Aal, Bahaa G. M. Youssif, Ola I. A. Salem

2022Journal of Molecular Structure24 citationsDOI

Topics & Concepts

ChemistryNorfloxacinDNA gyraseUreaseCiprofloxacinAntibacterial activityMinimum inhibitory concentrationEscherichia coliIC50BiochemistryBacteriaEnzymeAntibioticsIn vitroBiologyGeneGeneticsCancer therapeutics and mechanismsAntibiotic Resistance in BacteriaPneumocystis jirovecii pneumonia detection and treatment
Novel fluoroquinolone hybrids as dual DNA gyrase and urease inhibitors with potential antibacterial activity: Design, synthesis, and biological evaluation | Litcius