A Convenient and Biosafe Replicon with Accessory Genes of SARS-CoV-2 and Its Potential Application in Antiviral Drug Discovery
Yunyun Jin, Hanwen Lin, Liu Cao, Wei-Chen Wu, Yanxi Ji, Liubing Du, Yiling Jiang, Yanchun Xie, Kuijie Tong, Fan Xing, Fuxiang Zheng, Mǎng Shī, Ji-An Pan, Xiaoxue Peng, Deyin Guo
Topics & Concepts
RepliconBiologySubgenomic mRNAReverse geneticsViral replicationVirologyPlasmidGeneAntiviral drugRNARolling circle replicationComplementary DNAVirusGenomeComputational biologyGeneticsPolymeraseSARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologyBacteriophages and microbial interactions