DeORFanizing Candida albicans Genes using Coexpression
Teresa R. O’Meara, Matthew J. O’Meara
Abstract
Candida albicans is a common and deadly fungal pathogen of humans, yet the genome of this organism contains many genes of unknown function. By determining gene function, we can help identify essential genes, new virulence factors, or new regulators of drug resistance, and thereby give new targets for antifungal development.
Topics & Concepts
Candida albicansBiologyCorpus albicansGeneComputational biologyOpen reading frameFunction (biology)ORFSGeneticsGenomeModel organismPeptide sequenceAntifungal resistance and susceptibilityProbiotics and Fermented FoodsBioinformatics and Genomic Networks