The synthesis of PROTAC molecule and new target KAT6A identification of CDK9 inhibitor iCDK9
Mingtao Ao, Jun Wu, Yin Cao, Yaohui He, Yuxiang Zhang, Xiang Gao, Yuhua Xue, Meijuan Fang, Zhenhua Wu
Topics & Concepts
Small moleculeChemistryKinaseCereblonBiochemistryCell biologyUbiquitinBiologyGeneUbiquitin ligaseProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments