Ultrasensitive Detection of Nasopharyngeal Carcinoma-Related MiRNA through Garland Rolling Circle Amplification Integrated Catalytic Hairpin Assembly
Shayue Xu, Zhiping Lou
Abstract
enzymes. Afterward, a CHA process is induced with a designed H probe through the two signal amplification processes; the method exhibited a much-improved sensitivity. At last, we believe that this method is a promising approach capable of being applied in screening, diagnosing, and prognosticating multiple diseases.
Topics & Concepts
Nasopharyngeal carcinomaRolling circle replicationmicroRNABiomarkerSensitivity (control systems)SIGNAL (programming language)Computational biologyBiologyComputer scienceGeneMedicineGeneticsElectronic engineeringRadiation therapyInternal medicineDNA replicationProgramming languageEngineeringAdvanced biosensing and bioanalysis techniquesDendrimers and Hyperbranched PolymersSupramolecular Self-Assembly in Materials