Disulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper
Kelly C. Falls-Hubert, Aimee L. Butler, Kai Gui, Michael Anderson, Mengshi Li, Jeffrey M. Stolwijk, Samuel N. Rodman, Shane R. Solst, Ann Tomanek‐Chalkley, Charles Searby, Val C. Sheffield, Vanessa Sandfort, H Schmidt, Michael L. McCormick, Brian Wels, Bryan G. Allen, Garry R. Buettner, Michael K. Schultz, Douglas R. Spitz
Topics & Concepts
DisulfiramToxicityCancer cellCancer researchOxidative stressChemistryRadioresistancePharmacologyCarboplatinCancerTirapazamineMedicineChemotherapyRadiation therapyCytotoxicityCisplatinInternal medicineBiochemistryIn vitroOrganic chemistryHeme Oxygenase-1 and Carbon MonoxideCancer, Hypoxia, and MetabolismAlcohol Consumption and Health Effects