The gut microbiome and the immune system
Tenzin Choden, Nathaniel A. Cohen
Abstract
The human body contains trillions of microbes which generally live in symbiosis with the host. The interaction of the gut microbiome with elements of the host immune system has far-reaching effects in the development of normal gut and systemic immune responses. Disturbances to this intricate relationship may be responsible for a multitude of gastrointestinal and systemic immune mediated diseases. This review describes the development of the gut microbiome and its interaction with host immune cells in both health and disease states.
Topics & Concepts
Immune systemMicrobiomeGut microbiomeBiologyHost (biology)ImmunologyDiseaseBioinformaticsMedicineGeneticsPathologyGut microbiota and healthClostridium difficile and Clostridium perfringens researchGastrointestinal motility and disorders