Deoxygenative hydroboration of primary and secondary amides: a catalyst-free and solvent-free approach
Rohit Kumar, Milan Kumar Bisai, Shailja Jain, Kumar Vanka, Sakya S. Sen
Abstract
In contrast to the recent reports on catalytic hydroboration of amides to amines with pinacolborane (HBpin), a simple catalyst-free and solvent-free method for the hydroboration of a variety of amides has been realized. To get the mechanistic insights, DFT calculations have been performed.
Topics & Concepts
Primary (astronomy)CatalysisHydroborationChemistryOrganic chemistrySolventCombinatorial chemistryAstronomyPhysicsOrganoboron and organosilicon chemistryChemical Synthesis and AnalysisAsymmetric Hydrogenation and Catalysis