Higher-order interfiber interactions in the self-assembly of benzene-1,3,5-tricarboxamide-based peptides in water
Oleksandr Zagorodko, Tetiana Melnyk, Olivier Rogier, Vicent J. Nebot, Marı́a J. Vicent
Abstract
3 symmetry of benzene-1,3,5-tricarboxamide-based molecules in higher-order fibers becomes gradually distorted, thus facilitating hydrophobic contact interactions between fibrils. The proposed mechanism of self-assembly through hydrophobic contact allowed the successful design of a compound with pH-responsive morphology, and may find use in the future development of complex hierarchical architectures with controlled functionality.
Topics & Concepts
BenzeneOrder (exchange)ChemistryCombinatorial chemistryComputer scienceOrganic chemistryBusinessFinanceSupramolecular Self-Assembly in MaterialsChemical Synthesis and AnalysisPhotoreceptor and optogenetics research