Pediatric Inflammatory Multisystem Syndrome With Central Nervous System Involvement and Hypocomplementemia Following SARS-COV-2 Infection
Tslil Regev, Maayan Antebi, Danny Eytan, Yael Shachor‐Meyouhas, Anat Ilivitzki, Yonatan Butbul Aviel, Josef Ben‐Ari
Abstract
Pediatric inflammatory multisystem syndromes associated with Severe Acute Respiratory Syndrome Coronavirus 2 are emerging in recent reports. We describe a patient with critical illness consistent with atypical Kawasaki disease with cardiac dysfunction and abdominal involvement presenting weeks after Severe Acute Respiratory Syndrome Coronavirus 2 infection. Our patient showed unique central nervous system involvement with small vessel vasculitis and profound hypocomplementemia, both not previously reported in case descriptions and may hint at possible disease mechanisms.
Topics & Concepts
MedicineKawasaki diseaseVasculitisDiseaseCoronavirusCentral nervous systemImmunologyRespiratory systemMultisystem diseaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)PathologyInfectious disease (medical specialty)Internal medicineArteryKawasaki Disease and Coronary ComplicationsCOVID-19 Clinical Research StudiesCOVID-19 Impact on Reproduction