pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects
Lindomar J. C. Albuquerque, Vladimir Sincari, Alessandro Jäger, Jan Kučka, Jana Humajová, Jan Pankrác, Petr Páral, Tomáš Heizer, Olga Janoušková, Irina Davidovich, Yeshayahu Talmon, P Poučková, Petr Štěpánek, Luděk Šefc, Martin Hrubý, Fernando C. Giacomelli, Eliézer Jäger
Topics & Concepts
PolymersomeDoxorubicinChemistryDrug deliveryPharmacologyDrugTumor microenvironmentBiophysicsCancer researchChemotherapyTumor cellsMedicinePolymerBiologyInternal medicineCopolymerOrganic chemistryAmphiphileNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsLanthanide and Transition Metal Complexes