Telocytes enhanced in vitro decidualization and mesenchymal-epithelial transition in endometrial stromal cells via Wnt/β-catenin signaling pathway.
Fei-Lei Zhang, Yue-Lin Huang, Xiaoye Zhou, Xue-Ling Tang, Xiao‐Jun Yang
Abstract
< 0.05). This is the first study to show that TCs can enhance decidualization and MET in ESCs through the Wnt/β-catenin signaling-pathway. Therefore, we describe a promising cell therapy for gynecological conditions and related reproductive problems associated with defective decidualization.
Topics & Concepts
DecidualizationWnt signaling pathwayStromal cellCell biologyEndometriumBiologyInternal medicineCancer researchChemistryEndocrinologySignal transductionMedicineReproductive System and PregnancyEndometriosis Research and TreatmentGynecological conditions and treatments