Mitochondrion-targeting PEGylated BODIPY dyes for near-infrared cell imaging and photodynamic therapy
Isabel Wen Badon, Chanwoo Kim, Jong Min Lim, Duy Khuong, Temmy Pegarro Vales, Dongho Kang, Sung Cho, Joomin Lee, Ho‐Joong Kim, Jaesung Yang
Abstract
I enabled the dyes to localize and stain the negatively charged mitochondria. The results presented herein indicate the straightforward and facile synthesis of NIR-light triggered mitochondrion-targeting photosensitizers.
Topics & Concepts
Singlet oxygenPhotochemistryPhotodynamic therapyHeLaPhototoxicityQuantum yieldAbsorbanceBromineChemistryCytotoxicityMaterials sciencePhthalocyanineFluorescenceOxygenNanotechnologyOrganic chemistryCellIn vitroBiochemistryChromatographyQuantum mechanicsPhysicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies