Stepwise-activatable hypoxia triggered nanocarrier-based photodynamic therapy for effective synergistic bioreductive chemotherapy
Khan Malik Ihsanullah, Bejjanki Naveen Kumar, Yangyang Zhao, Muhammad Hassan, Yi Liu, Li Wang, Hang Liu, Wei Jiang
Topics & Concepts
TirapazaminePhotodynamic therapyPhotosensitizerProdrugTumor hypoxiaNanocarriersCancer researchTumor microenvironmentBiophysicsMaterials scienceDrug deliveryHypoxia (environmental)CytotoxicityChemistryNanotechnologyRadiation therapyTumor cellsBiochemistryMedicineIn vitroOxygenPhotochemistryBiologySurgeryOrganic chemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesCancer, Hypoxia, and Metabolism