DNA binding and evaluation of anticancer activity in vitro and in vivo of iridium(III) polypyridyl complexes
Yuanyuan Zhang, Yi Zhou, Huiwen Zhang, Tian Li, Jing Hao, Yuhan Yuan, Wenlong Li, Yunjun Liu
Topics & Concepts
ChemistryMolecular biologyApoptosisCell cycleCytotoxicityKinaseCyclin-dependent kinase 6PI3K/AKT/mTOR pathwayIn vivoStereochemistryCyclin D1In vitroBiochemistryBiologyBiotechnologyMetal complexes synthesis and propertiesQuinazolinone synthesis and applicationsCancer-related Molecular Pathways