A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
Stanislav Dikiy, Jun Li, Lu Bai, Menglin Jiang, Laura J. Janke, Xinying Zong, Xiaolei Hao, Beatrice Hoyos, Zhong-Min Wang, Beisi Xu, Yiping Fan, Alexander Y. Rudensky, Yongqiang Feng
Topics & Concepts
FOXP3STAT5BiologyAutoimmunityEnhancerIL-2 receptorImmunologyTranscription factorImmune toleranceRegulatory T cellCell biologyImmune systemT cellSignal transductionCancer researchGeneGeneticsT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune Responses