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The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization

Naoya Takayama, Alex Murison, Shin‐ichiro Takayanagi, Christopher Arlidge, Stanley Zhou, Laura García‐Prat, Michelle Chan‐Seng‐Yue, Sasan Zandi, Olga I. Gan, Héléna Boutzen, Kerstin B. Kaufmann, Aaron C. Trotman-Grant, Erwin M. Schoof, Ken J. Kron, Noèlia Díaz, John J. Y. Lee, Tiago da Silva Medina, Daniel D. De Carvalho, Michael D. Taylor, Juan M. Vaquerizas, Stephanie Z. Xie, John E. Dick, Mathieu Lupien

2020Cell stem cell100 citationsDOI

Topics & Concepts

BiologyChromatinCTCFStem cellHaematopoiesisCell biologyProgenitor cellGene silencingTranscription factorEmbryonic stem cellGeneticsGeneEnhancerHematopoietic Stem Cell TransplantationEpigenetics and DNA MethylationT-cell and B-cell Immunology
The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization | Litcius