Self-Assembled Nanosized Vehicles from Amino Acid-Based Amphiphilic Polymers with Pendent Carboxyl Groups for Efficient Drug Delivery
Wenli Feng, Zixuan Huang, Xiaoxu Kang, Dongdong Zhao, Haofei Li, Guofeng Li, Jiangtao Xu, Xing Wang
Abstract
-PD NPs exhibited rapid cellular uptake (within 1 min) and a great therapeutic performance. These drug delivery systems provide new insights for regulating the controlled morphologies and improving the efficiency of drug delivery.
Topics & Concepts
AmphiphileCopolymerBiocompatibilityDrug deliveryMonomerChemistryCombinatorial chemistryNanoparticlePolymerPolymerizationPolymer chemistryMaterials scienceOrganic chemistryNanotechnologyAdvanced Polymer Synthesis and CharacterizationNanoparticle-Based Drug DeliveryDendrimers and Hyperbranched Polymers