Synthesis of (<i>E</i>)-Quinoxalinone Oximes through a Multicomponent Reaction under Mild Conditions
Jun Xu, Huiyong Yang, Lei He, Lin Huang, Jiabin Shen, Wanmei Li, Pengfei Zhang
Abstract
)-oximes in a moderate-to-good yield through recrystallization. Our methodology demonstrates a successful combination of a Mannich-type reaction and radical coupling, providing a green and practical approach for the synthesis of potentially bioactive quinoxalinone-containing molecules.
Topics & Concepts
ChemistryYield (engineering)Recrystallization (geology)Mannich reactionReaction conditionsOrganic chemistryOximeCombinatorial chemistryCoupling reactionMoleculeCatalysisMetallurgyPaleontologyBiologyMaterials scienceSynthesis and Biological EvaluationCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques