Near-infrared absorbing Ru(<scp>ii</scp>) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma
Liubov M. Lifshits, John A. Roque, Prathyusha Konda, Susan Monro, Houston D. Cole, David von Dohlen, Susy Kim, Gagan Deep, Randolph P. Thummel, Colin G. Cameron, Shashi Gujar, Sherri A. McFarland
Abstract
and challenged with live B16F10 cells exhibited 80 and 55% protection from tumor growth, respectively, leading to significantly improved survival and excellent hazard ratios of ≤0.2.
Topics & Concepts
Photodynamic therapyMelanomaChemistryCancer researchMedicinePhotochemistryOrganic chemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesGold and Silver Nanoparticles Synthesis and Applications