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Hidden Resistances: How Routine Whole-Genome Sequencing Uncovered an Otherwise Undetected <i>bla</i> <sub>NDM-1</sub> Gene in Vibrio alginolyticus from Imported Seafood

Jacqueline M. Morris, Karolina Mercoulia, Mary Valcanis, Claire L. Gorrie, Norelle L. Sherry, Benjamin P. Howden

2023Microbiology Spectrum11 citationsDOIOpen Access PDF

Abstract

gene, and there is the potential for transmission of resistance genes. This may be linked with antimicrobial use in low- and middle-income settings, which has typically been high, unregulated, or not reported. Many countries, including Thailand, have implemented national strategic plans to incorporate the World Health Organization (WHO)'s Global Action Plan (2015) recommendations of a global One Health approach, including increased resources for surveillance of antimicrobial usage and AMR; however, efficient antimicrobial surveillance systems incorporating genomic and phenotypic testing of isolates are still lacking in many jurisdictions.

Topics & Concepts

Vibrio alginolyticusBiologyMicrobiologyGeneMultiple drug resistanceCarbapenemGeneticsKlebsiella pneumoniaeAntibiotic resistanceVibrioDrug resistanceBacteriaEscherichia coliAntibioticsAntibiotic Resistance in BacteriaVibrio bacteria research studiesPharmaceutical and Antibiotic Environmental Impacts
Hidden Resistances: How Routine Whole-Genome Sequencing Uncovered an Otherwise Undetected <i>bla</i> <sub>NDM-1</sub> Gene in Vibrio alginolyticus from Imported Seafood | Litcius