Automated QuEChERS for the determination of 482 pesticide residues in Radix codonopsis by GC-Q-TOF/MS and LC-Q-TOF/MS
Qiaoying Chang, Lijuan Ge, Jian Li, Guoyu Qiu, Fuxiang Wu, Hongyan Zhang, Fenghua Xu, Renyuan Zhu, Pengfei Qi, Ruobin Bai, Fazheng Ren
Abstract
424. Besides, the automated workstation presented lower RSD (more pesticides ≤10%) and better recovery quality (more pesticides within 90-110%). Following the method verification, 50 Radix codonopsis samples purchased from local markets were prepared with the automated workstation and analyzed by GC and LC-Q-TOF/MS. 18 pesticides were detected in 38 samples, one of which was a highly toxic pesticide. The automated QuEChERS workstation can handle 40 samples in one cycle within 6 hours, and realize whole-process automation covering from samples after "weighing" to "injection into vials". The batch-to-batch, day-to-day, and lab-to-lab consistency and 24 × 7 workability of the automated solution have demonstrated a promising and ideal replacement for manual operation in sample preparation.