Exploring the binding mechanism of β-resorcylic acid with calf thymus DNA: Insights from multi-spectroscopic, thermodynamic and bioinformatics approaches
Irfan Hussain, Sana Fatima, Sharmin Siddiqui, Shahbaz Ahmed, Mohammad Tabish
Topics & Concepts
Isothermal titration calorimetryChemistryCircular dichroismDNABinding constantQuenching (fluorescence)Molecular modelHydrogen bondMolecular dynamicsHydrophobic effectMoleculeCrystallographyBiophysicsStereochemistryBinding siteComputational chemistryBiochemistryFluorescenceOrganic chemistryQuantum mechanicsPhysicsBiologyProtein Interaction Studies and Fluorescence AnalysisMetal complexes synthesis and propertiesDrug Transport and Resistance Mechanisms