An efficient synthesis of mono-, di-, and tri-substituted 1,3-thiazoles employing functionalized thioamides as thiocarbonyl precursors
Kalleshappa Sheela, Chikkappaiahnayaka Santhosh, Krishna Ravi Singh, Kalleshappa Sharath, Maralinganadoddi P. Sadashiva
Abstract
Herein, we report an efficient strategy to synthesize functionalized 1,3-thiazoles using alkyl 2-amino-2-thioxoacetates.
Topics & Concepts
AlkylCombinatorial chemistryChemistryOrganic chemistrySynthesis of heterocyclic compoundsSynthesis and Reactivity of Sulfur-Containing CompoundsSynthesis and biological activity