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Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy

Karrune Woan, Hansol Kim, Ryan Bjordahl, Zachary Davis, Svetlana Gaidarova, John Goulding, Brian Hancock, Sajid Mahmood, Ramzey Abujarour, Hongbo Wang, Katie Tuininga, Bin Zhang, Cheng‐Ying Wu, Behiye Kodal, Melissa Khaw, Laura E. Bendzick, Paul Rogers, Moyar Ge, Greg Bonello, Miguel Meza, Martin Felices, Janel Huffman, Thomas Dailey, Tom T. Lee, Bruce Walcheck, Karl‐Johan Malmberg, Bruce R. Blazar, Yenan T. Bryceson, Bahram Valamehr, Jeffrey S. Miller, Frank Cichocki

2021Cell stem cell154 citationsDOIOpen Access PDF

Topics & Concepts

BiologyInduced pluripotent stem cellImmune systemImmunotherapyCell biologyCancer immunotherapyEffectorChimeric antigen receptorInterleukin 12ImmunologyCancer researchCytotoxic T cellGeneIn vitroGeneticsEmbryonic stem cellCAR-T cell therapy researchImmune Cell Function and InteractionCRISPR and Genetic Engineering
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy | Litcius