Hypoxia-inducible factor-1 alpha (HIF-1α) inhibitor AMSP-30 m attenuates CCl4-induced liver fibrosis in mice by inhibiting the sonic hedgehog pathway
Long‐Sheng Lu, Yuchen Ma, Qing Tao, Jing Xie, Xiao Liu, Yongkang Wu, Yang Zhang, Xiuli Xie, Mingming Liu, Yong Jin, Yong Jin
Topics & Concepts
HedgehogHedgehog signaling pathwaySonic hedgehogHypoxia-Inducible Factor 1Hypoxia (environmental)Liver fibrosisAlpha (finance)CCL4PharmacologyHypoxia-inducible factorsChemistryMedicineCancer researchFibrosisBiologyCell biologyInternal medicineSignal transductionBiochemistryTranscription factorOxygenCarbon tetrachlorideSurgeryGeneConstruct validityOrganic chemistryPatient satisfactionLiver physiology and pathologyCancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation