Litcius/Paper detail

Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine

Mason Daniel Hurd, Isha Goel, Yasuyuki Sakai, Yuji Teramura

2021Regenerative Therapy62 citationsDOIOpen Access PDF

Abstract

Ischemic stroke is a major cause of death and disability worldwide and is expected to increase in the future with the aging population. Currently, there are no clinically available treatments for damage sustained during an ischemic stroke, but much research is being conducted in this area. In this review, we will introduce current ischemic stroke treatments along with their limitations, as well as research on potential short and long-term future treatments. There are advantages and disadvantages in these potential treatments, but our understanding of these methods and their effectiveness in clinical trials are improving. We are confident that some future treatments introduced in this review will become commonly used in clinical settings in the future.

Topics & Concepts

MedicineStroke (engine)ThrombolysisIntensive care medicineClinical trialIschemic strokeCause of deathPopulationRegenerative medicineInternal medicineIschemiaDiseaseMyocardial infarctionStem cellMechanical engineeringBiologyEnvironmental healthEngineeringGeneticsAcute Ischemic Stroke ManagementExtracellular vesicles in diseaseNeuroinflammation and Neurodegeneration Mechanisms