Litcius/Paper detail

Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors

Tarek S. Ibrahim, Riham M. Bokhtia, Amany M. M. Al‐Mahmoudy, Ehab S. Taher, Mohammed A. AlAwadh, Mohamed Elagawany, Eatedal H. Abdel‐Aal, Siva S. Panda, Ahmed M. Gouda, Hany Z. Asfour, Nabil A. Alhakamy, Bahaa G. M. Youssif

2020Bioorganic Chemistry42 citationsDOI

Topics & Concepts

ChemistryMethyleneStereochemistryEC50SelectivityDocking (animal)Proton NMRIn vitroMedicinal chemistryOrganic chemistryBiochemistryCatalysisNursingMedicineHIV/AIDS drug development and treatmentHIV Research and TreatmentPneumocystis jirovecii pneumonia detection and treatment