Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors
Tarek S. Ibrahim, Riham M. Bokhtia, Amany M. M. Al‐Mahmoudy, Ehab S. Taher, Mohammed A. AlAwadh, Mohamed Elagawany, Eatedal H. Abdel‐Aal, Siva S. Panda, Ahmed M. Gouda, Hany Z. Asfour, Nabil A. Alhakamy, Bahaa G. M. Youssif
Topics & Concepts
ChemistryMethyleneStereochemistryEC50SelectivityDocking (animal)Proton NMRIn vitroMedicinal chemistryOrganic chemistryBiochemistryCatalysisNursingMedicineHIV/AIDS drug development and treatmentHIV Research and TreatmentPneumocystis jirovecii pneumonia detection and treatment