Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice
Neele Schumacher, Isabell Yan, Monja Gandraß, Miryam Müller, Christoph Krisp, Robert Häsler, Antonella Carambia, Jerzy–Roch Nofer, Joanna P. Bernardes, Mouhamad Khouja, Ilka Thomsen, Karel Chalupský, Julia Bolik, Christoph Hölscher, Thomas Wunderlich, Johannes Herkel, Philip Rosenstiel, Christoph Schramm, Hartmut Schlüter, Thomas Renné, Hans‐Willi Mittrücker, Stefan Rose‐John, Dirk Schmidt‐Arras
Topics & Concepts
BiologyInnate immune systemCell biologyProgenitor cellImmunologyGlycoprotein 130HepatocyteHepatic stellate cellImmune systemCytokineCancer researchStem cellInterleukin 6EndocrinologyIn vitroBiochemistryCytokine Signaling Pathways and InteractionsT-cell and B-cell ImmunologyNF-κB Signaling Pathways